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Tissue Transglutaminase Screening (IgA)
Tissue Transglutaminase Screening (IgA)
SKU:TTG
Unexplained bloating, diarrhoea, fatigue, or nutrient deficiencies may signal coeliac disease. The Tissue Transglutaminase (IgA) Test checks for IgA antibodies that attack the small intestine in response to gluten, making it one of the most reliable markers for coeliac disease.
Why the Tissue Transglutaminase (IgA) Test Matters?
Detecting IgA antibodies helps identify autoimmune activity against gluten. This test is widely used to screen for coeliac disease, enabling earlier diagnosis, treatment with a gluten-free diet, and prevention of long-term complications such as malnutrition and intestinal damage.
What Gets Assessed?
- IgA antibodies against tissue transglutaminase
50 in stock
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Visit a partner clinic (+£50)
Once you've ordered your test, look out for an email from our phlebotomy partners containing information and a link to book your appointment. We'll send you everything the clinic will need to complete the sample and post it back to our labs.
Organise a nurse myself (FREE)
If none of the above options work for you, you can arrange your own medical professional to collect your sample. There is no additional charge for this. Once you've ordered your test, we'll send you everything you and your chosen medical professional will need to collect a sample and post it back to our labs.
FAQs
What does the Tissue Transglutaminase (tTG IgA) Test measure?
The tTG IgA test measures IgA antibodies against tissue transglutaminase, an enzyme targeted in coeliac disease. Elevated levels indicate an autoimmune reaction to gluten.
Who should consider this coeliac disease test?
This test is recommended for individuals with persistent digestive problems, malabsorption, nutrient deficiencies, unexplained fatigue, skin rashes, or a family history of coeliac disease.
How is the sample collected?
The test requires a simple venous blood draw, which is then analysed in a laboratory to check for tTG IgA antibodies.
What do positive Tissue Transglutaminase IgA results mean?
A positive result strongly suggests coeliac disease or gluten intolerance. However, additional tests, such as an intestinal biopsy, may be recommended to confirm the diagnosis.
Can a gluten-free diet affect test results?
Yes. Starting a gluten-free diet before testing can lower antibody levels, leading to false negatives. For accurate results, you should continue eating gluten until after the test.
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